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1

Involvement of microbial respiratory pathogens in acute interstitial pneumonia in feedlot cattle

Loneragan, Guy H., Gould, Daniel H., Mason, Gary L., Garry, Franklyn B., Yost, Garold S., Miles, Delbert G., Hoffman, Bruce W., Mills, Leon J.

Journal:

American Journal of Veterinary Research

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

2

Low-dose paroxetine exposure causes lifetime declines in male mouse body weight, reproduction and competitive ability as measured by the novel organismal performance assay

Gaukler, Shannon M., Ruff, James S., Galland, Tessa, Kandaris, Kirstie A., Underwood, Tristan K., Liu, Nicole M., Young, Elizabeth L., Morrison, Linda C., Yost, Garold S., Potts, Wayne K.

Journal:

Neurotoxicology and Teratology

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

3

Miserotoxin, a toxic compound in Astragalus michauxii

M.Coburn Williams, Garold S. Yost, Frank R. Stermitz

Journal:

Year:

1977

Language:

english

File:

PDF, 213 KB

english, 1977

4

Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts

John M Veranth, Erin G Kaser, Martha M Veranth, Michael Koch, Garold S Yost

Journal:

Particle and Fibre Toxicology

Year:

2007

Language:

english

File:

PDF, 471 KB

english, 2007

5

Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1

Patrick L. Sheets, Garold S. Yost, Gary P. Carlson

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2004

Language:

english

File:

PDF, 142 KB

english, 2004

6

Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells

Christopher A. Reilly, Mark E. Johansen, Diane L. Lanza, Jeewoo Lee, Ju-Ok Lim, Garold S. Yost

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2005

Language:

english

File:

PDF, 184 KB

english, 2005

7

Localization of CYP4B1 in the rat nasal cavity and analysis of CYPs as secreted proteins

Mary Beth Genter, Garold S. Yost, Allan E. Rettie

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

8

Quantum mechanically derived AMBER-compatible heme parameters for various states of the cytochrome P450 catalytic cycle

Kiumars Shahrokh, Anita Orendt, Garold S. Yost, Thomas E. Cheatham III

Journal:

Journal of Computational Chemistry

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

9

Determination of capsaicin, dihydrocapsaicin, and nonivamide in self-defense weapons by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry

Christopher A. Reilly, Dennis J. Crouch, Garold S. Yost, Alim A. Fatah

Journal:

Journal of Chromatography A

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

10

Toxic furocoumarins of Cymopterus longipes

Garold S. Yost, Frank R. Stermitz, M. Coburn Williams

Journal:

Year:

1977

Language:

english

File:

PDF, 111 KB

english, 1977

11

A novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation

Cassandra E Deering, Soheyl Tadjiki, Shoeleh Assemi, Jan D Miller, Garold S Yost, John M Veranth

Journal:

Particle and Fibre Toxicology

Year:

2008

Language:

english

File:

PDF, 1.66 MB

english, 2008

12

Production and Characterization of Specific Antibodies: Utilization to Predict Organ- and Species-Selective Pneumotoxicity of 3-Methylindole

JuLee K. Kaster, Garold S. Yost

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 427 KB

english, 1997

13

Glutathione adduct formation with microsomally activated metabolites of the pulmonary alkylating and cytotoxic agent, 3-methylindole

Mark R. Nocerini, James R. Carlson, Garold S. Yost

Journal:

Toxicology and Applied Pharmacology

Year:

1985

Language:

english

File:

PDF, 935 KB

english, 1985

14

Procarbazine spermatogenesis toxicity: Deuterium isotope effects point to regioselective metabolism in mice

Garold S. Yost, Michael G. Horstman, Abdel Fattah El Walily, W.Perry Gordon, Sidney D. Nelson

Journal:

Toxicology and Applied Pharmacology

Year:

1985

Language:

english

File:

PDF, 620 KB

english, 1985

15

Decreased pneumotoxicity of deuterated 3-methylindole: Bioactivation requires methyl CH bond breakage

Jeannette C. Huijzer, James D. Adams Jr., Garold S. Yost

Journal:

Toxicology and Applied Pharmacology

Year:

1987

Language:

english

File:

PDF, 1.53 MB

english, 1987

16

Mechanisms of lung injury by systemically administered chemicals

Garold S. Yost, Alan R. Buckpitt, Robert A. Roth, Theodore L. McLemore

Journal:

Toxicology and Applied Pharmacology

Year:

1989

Language:

english

File:

PDF, 1.50 MB

english, 1989

17

Organ-selective switching of 3-methylindole toxicity by glutathione depletion

Garold S. Yost, David J. Kuntz, Lawrence D. McGill

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 4.97 MB

english, 1990

18

Isolation of a mercapturate adduct produced subsequent to glutathione conjugation of bioactivated 3-methylindole

Gary L. Skiles, David J. Smith, Martin L. Appleton, James R. Carlson, Garold S. Yost

Journal:

Toxicology and Applied Pharmacology

Year:

1991

Language:

english

File:

PDF, 534 KB

english, 1991

19

Effects of the differentiated keratinocyte phenotype on expression levels of CYP1–4 family genes in human skin cells

Liping Du, Mark M. Neis, Patricia A. Ladd, Diane L. Lanza, Garold S. Yost, Diane S. Keeney

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 448 KB

english, 2006

20

Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action

Kenneth T. Bogen, Janet M. Benson, Garold S. Yost, John B. Morris, Alan R. Dahl, Harvey J. Clewell III, Kannan Krishnan, Curtis J. Omiecinski

Journal:

Regulatory Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

21

Bioactivation of Halogenated Hydrocarbons by Rabbit Pulmonary Cells

William K. Nichols, Mark O. Covington, Christopher D. Seiders, Shaheen Safiullah, Garold S. Yost

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1992

Language:

english

File:

PDF, 629 KB

english, 1992

22

Directed Evolution Reveals Requisite Sequence Elements in the Functional Expression of P450 2F1 in Escherichia coli

Behrendorff, James B. Y. H., Moore, Chad D., Kim, Keon-Hee, Kim, Dae-Hwan, Smith, Christopher A., Johnston, Wayne A., Yun, Chul-Ho, Yost, Garold S., Gillam, Elizabeth M. J.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.85 MB

english, 2012

23

Metabolism of Capsaicin by Cytochrome P450 Produces Novel Dehydrogenated Metabolites and Decreases Cytotoxicity to Lung and Liver Cells

Reilly, Christopher A., Ehlhardt, William J., Jackson, David A., Kulanthaivel, Palaniappan, Mutlib, Abdul E., Espina, Robert J., Moody, David E., Crouch, Dennis J., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 593 KB

english, 2003

24

Cloning and Expression of CYP2F3,a Cytochrome P450 That Bioactivates the Selective Pneumotoxins 3-Methylindole and Naphthalene

Huifen Wang, Diane L. Lanza, Garold S. Yost

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 363 KB

english, 1998

25

Destruction of cytochrome P-450 by 2-isopropyl-4-pentenamide and methyl 2-isopropyl-4-pentenoate: Mass spectrometric characterization of prosthetic heme adducts and nonparticipation of epoxide metabolites

Paul R.Ortiz De Montellano, Garold S. Yost, Bruce A. Mico, Stephen E. Dinizo, M.Almira Correia, Hidaeki Kumbara

Journal:

Archives of Biochemistry and Biophysics

Year:

1979

Language:

english

File:

PDF, 979 KB

english, 1979

26

Purification and characterization of an ethanol-induced UDP-glucuronosyltransferase

Renta M. Hutabarat, Garold S. Yost

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 1.12 MB

english, 1989

27

3-methylindole inhibits lipid peroxidation

James D. Adams Jr., Mikel C. Heins, Garold S. Yost

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 401 KB

english, 1987

28

Substrate-selective induction of rabbit hepatic UDP-glucuronyltransferases by ethanol and other xenobiotics

Brent L. Finley, Patrick J. Ashley, Andre G. Neptune, Garold S. Yost

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 866 KB

english, 1986

29

Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen

Kiumars Shahrokh, Thomas E. Cheatham III, Garold S. Yost

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

30

Effects of cell type and culture media on Interleukin-6 secretion in response to environmental particles

John M. Veranth, N. Shane Cutler, Erin G. Kaser, Christopher A. Reilly, Garold S. Yost

Journal:

Toxicology in Vitro

Year:

2008

Language:

english

File:

PDF, 407 KB

english, 2008

31

Metabolic activation of the pneumotoxin, 3-methylindole, by vaccinia-expressed cytochrome P450s

Janice R. Thornton-Manning, Werawan Ruangyuttikarn, Frank J. Gonzalez, Garold S. Yost

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 544 KB

english, 1991

32

Ethanol as an inducer of UDP-glucuronyltransferase: A comparison with phenobarbital and 3-methylcholanthrene induction in rabbit hepatic microsomes

Garold S. Yost, Brent L. Finley

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 251 KB

english, 1983

33

Suicidal inactivation of cytochrome P-450. Formation of a heme-substrate covalent adduct

Paul R.Ortiz de Montellano, Bruce A. Mico, Garold S. Yost

Journal:

Biochemical and Biophysical Research Communications

Year:

1978

Language:

english

File:

PDF, 327 KB

english, 1978

34

Fluticasone Propionate Pharmacogenetics: CYP3A4*22 Polymorphism and Pediatric Asthma Control

Stockmann, Chris, Fassl, Bernhard, Gaedigk, Roger, Nkoy, Flory, Uchida, Derek A., Monson, Steven, Reilly, Christopher A., Leeder, J. Steven, Yost, Garold S., Ward, Robert M.

Journal:

The Journal of Pediatrics

Year:

2013

Language:

english

File:

PDF, 493 KB

english, 2013

35

CYP3A4-Mediated Oxygenation versus Dehydrogenation of Raloxifene

Moore, Chad D., Reilly, Christopher A., Yost, Garold S.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

36

Improved Cytochrome P450 3A4 Molecular Models Accurately Predict the Phe215 Requirement for Raloxifene Dehydrogenation Selectivity

Moore, Chad D., Shahrokh, Kiumars, Sontum, Stephen F., Cheatham, Thomas E., Yost, Garold S.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.89 MB

english, 2010

37

Zafirlukast Metabolism by Cytochrome P450 3A4 Produces an Electrophilic α,β-Unsaturated Iminium Species That Results in the Selective Mechanism-Based Inactivation of the Enzyme

Kassahun, Kelem, Skordos, Konstantine, McIntosh, Ian, Slaughter, Donald, Doss, George A., Baillie, Thomas A., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

38

Metabolism of Capsaicinoids by P450 Enzymes: A Review of Recent Findings on Reaction Mechanisms, Bio-Activation, and Detoxification Processes*

Reilly, Christopher A., Yost, Garold S.

Journal:

Drug Metabolism Reviews

Year:

2006

Language:

english

File:

PDF, 509 KB

english, 2006

39

Adducts of 3-methylindole and glutathione: Species differences in organ-selective bioactivation

Nocerini, Mark R., Carlson, James R., Yost, Garold S.

Journal:

Toxicology Letters

Year:

1985

Language:

english

File:

PDF, 619 KB

english, 1985

40

Correlation between pulmonary cytochrome P450 transcripts and the organ-selective pneumotoxicity of 3-methylindole

Ramakanth, Swayampakula, Thornton-Manning, Janice R., Huifen, Wang, Maxwell, Heather, Yost, Garold S.

Journal:

Toxicology Letters

Year:

1994

Language:

english

File:

PDF, 834 KB

english, 1994

41

Self-Catalyzed Destruction of Cytochrome P-450: Covalent Binding of Ethynyl Sterols to Prosthetic Heme

Paul R. Ortiz De Montellano, Kent L. Kunze, Garold S. Yost and Bruce A. Mico

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 637 KB

english, 1979

42

Correlation of in Vitro Cytokine Responses with the Chemical Composition of Soil-Derived Particulate Matter

John M. Veranth, Tyler A. Moss, Judith C. Chow, Raed Labban, William K. Nichols, John C. Walton, John G. Watson and Garold S. Yost

Journal:

Environmental Health Perspectives

Year:

2006

File:

PDF, 3.07 MB

2006

43

Single Mutations Change CYP2F3 From a Dehydrogenase of 3-Methylindole to an Oxygenase †

Kartha, Jaya S., Skordos, Konstantine W., Sun, Hao, Hall, Clifton, Easterwood, LaHoma M., Reilly, Christopher A., Johnson, Eric F., Yost, Garold S.

Journal:

Year:

2008

Language:

english

File:

PDF, 2.37 MB

english, 2008

44

Isolation and identification of 3-hydroxy-3-methyloxindole, the major murine metabolite of 3-methylindole

Skiles, Gary L., Adams, James D., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

1989

Language:

english

File:

PDF, 694 KB

english, 1989

45

Detection and Characterization of DNA Adducts of 3-Methylindole

Regal, Kelly A., Laws, George M., Yuan, Cai, Yost, Garold S., Skiles, Gary L.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 372 KB

english, 2001

46

Potent Mutagenicity of 3-Methylindole Requires Pulmonary Cytochrome P450-Mediated Bioactivation: A Comparison to the Prototype Cigarette Smoke Mutagens B(a)P and NNK

Weems, Jessica M., Lamb, John G., D’Agostino, Jaime, Ding, Xinxin, Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 3.64 MB

english, 2010

47

3-Methylindole Metabolites Induce Lung CYP1A1 and CYP2F1 Enzymes by AhR and Non-AhR Mechanisms, Respectively

Weems, Jessica M., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 2.34 MB

english, 2010

48

Reactive Intermediates Produced from the Metabolism of the Vanilloid Ring of Capsaicinoids by P450 Enzymes

Reilly, Christopher A., Henion, Fred, Bugni, Tim S., Ethirajan, Manivannan, Stockmann, Chris, Pramanik, Kartick C., Srivastava, Sanjay K., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 2.73 MB

english, 2013

49

Mechanistic Studies on the Cytochrome P450-Catalyzed Dehydrogenation of 3-Methylindole

Skiles, Gary L., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 206 KB

english, 1996

50

The Inhaled Glucocorticoid Fluticasone Propionate Efficiently Inactivates Cytochrome P450 3A5, a Predominant Lung P450 Enzyme

Murai, Takahiro, Reilly, Christopher A., Ward, Robert M., Yost, Garold S.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 263 KB

english, 2010

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